2: Recent advances in therapy of diabetes.

Publisher: Australasian Medical Publishing Co Country of Publication: Australia NLM ID: 0400714 Publication Model: Print Cited Medium: Print ISSN: 0025-729X (Print) Linking ISSN: 0025729X NLM ISO Abbreviation: Med J Aust Subsets: MEDLINE

Publication: : Pyrmont, NSW : Australasian Medical Publishing Co.
Original Publication: Sydney : Australasian Medical Pub. Co.

Diabetes Mellitus, Type 1/*therapy ; Diabetes Mellitus, Type 2/*therapy; Adolescent ; Adult ; Anti-Obesity Agents/therapeutic use ; Blood Glucose Self-Monitoring/instrumentation ; Blood Glucose Self-Monitoring/methods ; Child ; Drug Administration Schedule ; Female ; Humans ; Insulin/analogs & derivatives ; Insulin/therapeutic use ; Insulin Infusion Systems ; Lactones/therapeutic use ; Male ; Middle Aged ; Orlistat ; Patient Education as Topic/methods ; Receptors, Cytoplasmic and Nuclear/agonists ; Transcription Factors/agonists

As suboptimal blood glucose control has a lasting harmful effect even if control improves later, intensive insulin therapy to minimise hyperglycaemia is now recommended for all patients with type 1 diabetes. The new rapid- and long-acting insulin analogues offer more physiological insulin profiles than traditional insulin preparations. Continuous insulin infusion ("pump therapy") may provide a solution for some patients with frequent hypoglycaemia or hypoglycaemic unawareness. Continuous blood glucose monitoring reveals postprandial hyperglycaemia and asymptomatic nocturnal hypoglycaemia and may be especially useful for programming overnight basal insulin rates for pump therapy. In type 2 diabetes, management should change with disease progression; introduction of insulin should not be delayed if metabolic control becomes suboptimal.

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Comment in: Med J Aust. 2004 Apr 5;180(7):368. (PMID: 15059063)

0 (Anti-Obesity Agents)
0 (Insulin)
0 (Lactones)
0 (Receptors, Cytoplasmic and Nuclear)
0 (Transcription Factors)
95M8R751W8 (Orlistat)

Date Created: 20031016 Date Completed: 20040108 Latest Revision: 20201219

20221213

10.5694/j.1326-5377.2003.tb05628.x

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