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[Effect of nitrobenzoic acid on methemoglobin content in blood and activity of antioxidative enzymes in erythrocytes].
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- Author(s): Shugaleĭ IV; Tselinskiĭ IV; Dolmatov VIu
- Source:
Ukrainskii biokhimicheskii zhurnal (1978) [Ukr Biokhim Zh (1978)] 1992 Jul-Aug; Vol. 64 (4), pp. 98-101.
- Publication Type:
English Abstract; Journal Article
- Language:
Russian
- Additional Information
- Transliterated Title:
Vliianie nitrobenzoĭnykh kislot na soderzhanie metgemoglobina v krovi i aktivnost' antiokislitel'nykh fermentov éritrotsitov.
- Source:
Publisher: Izdatelstvo Naukova Dumka Country of Publication: Ukraine NLM ID: 7804246 Publication Model: Print Cited Medium: Print ISSN: 0201-8470 (Print) Linking ISSN: 02018470 NLM ISO Abbreviation: Ukr Biokhim Zh (1978) Subsets: MEDLINE
- Publication Information:
Original Publication: Kiev : Izdatelstvo Naukova Dumka
- Subject Terms:
- Abstract:
Intraperitoneal administration of meta-nitrobenzoic, 3,5-dinitrobenzoic, 2,4,6-trinitrobenzoic and 3,5-dinitro-4-methylbenzoic acids to the white mice in a dose equal to LD50 has induced an increase in the methaemoglobin content in their blood. Total activity of dehydrogenases of pentosephosphate pathway, content of 2,3-diphosphoglycerate increase in response to the intoxication evoked by the mentioned acids. The acute intoxication does not practically change the activity of the key enzymes of antioxidant protection: superoxide-dismutase, catalase and glutathione peroxidase.
- Accession Number:
0 (Diphosphoglyceric Acids)
0 (Nitrobenzoates)
138-81-8 (2,3-Diphosphoglycerate)
9008-37-1 (Methemoglobin)
EC 1.11.1.6 (Catalase)
EC 1.11.1.9 (Glutathione Peroxidase)
EC 1.15.1.1 (Superoxide Dismutase)
- Publication Date:
Date Created: 19920701 Date Completed: 19921224 Latest Revision: 20150505
- Publication Date:
20240829
- Accession Number:
1448880
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