Mutant Mice Shed New Light on; Cause of Aortic Aneurysms in Marfan Syndrome Sufferers

Scientists have for the first time created mice with a genetic condition that resembles Marfan syndrome, a potentially fatal hereditary connective tissue disorder that weakens tissues of the skeleton, eyes, lungs, heart and blood vessels. Analyses of the mice provide an unexpected new view of the connective tissue defects, especially aortic aneurysms, that occur in people with Marfan syndrome...