Congenital malformations in hamster embryos after treatment with vinblastine and vincristine.

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  • Author(s): FERM VH
  • Source:
    Science (New York, N.Y.) [Science] 1963 Aug 02; Vol. 141 (3579), pp. 426.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Print ISSN: 0036-8075 (Print) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: OLDMEDLINE
    • Publication Information:
      Publication: : Washington, DC : American Association for the Advancement of Science
      Original Publication: New York, N.Y. : [s.n.] 1880-
    • Subject Terms:
      Antineoplastic Agents* ; Congenital Abnormalities* ; Embryo, Mammalian* ; Embryo, Nonmammalian* ; Fetus* ; Vinblastine* ; Vincristine*; Animals ; Cricetinae ; Female ; Pregnancy
    • Abstract:
      Intravenous injection of vinblastine or vincristine, two antitumor chemotherapeutic agents used in humans, into pregnant golden hamsters on the 8th day of gestation, causes an increase in the fetal mortality rate and the appearance of a significant number of congenital malformations in the surviving fetuses.
    • Contributed Indexing:
      Keywords: ABNORMALITIES*; ANTINEOPLASTIC AGENTS*; EMBRYO*; VINBLASTINE*
    • Accession Number:
      0 (Antineoplastic Agents)
      5J49Q6B70F (Vincristine)
      5V9KLZ54CY (Vinblastine)
    • Publication Date:
      Date Created: 19630802 Date Completed: 19981101 Latest Revision: 20190619
    • Publication Date:
      20221213
    • Accession Number:
      10.1126/science.141.3579.426
    • Accession Number:
      13944772