[The role of lactate acidosis and enzyme hyperactivity in evaluating hypoxic organ disorders in patients following cardiopulmonary byøass].

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  • Additional Information
    • Transliterated Title:
      Rol' laktatatsidoza i giperfermentemii v otsenke gipoksicheskikh organnykh povrezhdeniĭ u bol'nykh, operirovannykh na serdtse v usloviiakh iskusstvennogo krovoobrashcheniia.
    • Source:
      Publisher: Meditsina Country of Publication: Russia (Federation) NLM ID: 7705399 Publication Model: Print Cited Medium: Print ISSN: 0201-7563 (Print) Linking ISSN: 02017563 NLM ISO Abbreviation: Anesteziol Reanimatol Subsets: MEDLINE
    • Publication Information:
      Publication: Moskva : Meditsina
      Original Publication: Moskva, Meditsina.
    • Subject Terms:
    • Abstract:
      One hundred and fifty patients after cardiopulmonary bypass surgery have been examined. It has been shown that overall enzyme activity should be taken into consideration when determining the genesis of postoperative hyperenzymemia and diagnosing the topical (organic) damage. High lactate level (6-8 mmol/l) reflects profound circulatory hypoxia and shows a great likelihood of secondary damage of parenchymatous organs in patients after cardiopulmonary bypass surgery. Marked lactatacidosis combined with a 5-10-fold increase in enzyme activity in the early postoperative period is an unfavourable prognostic sign. Prolonged antagosan (trasilol) administration during cardiopulmonary bypass surgery may be one of the techniques preventing and correcting hypoxic organ damage.
    • Accession Number:
      9087-70-1 (Aprotinin)
    • Publication Date:
      Date Created: 19920301 Date Completed: 19921026 Latest Revision: 20161123
    • Publication Date:
      20240829
    • Accession Number:
      1384400