Vyzulta® as First-line Treatment for Patients with Open-angle Glaucoma and Ocular Hypertension.

The article discusses the application of Vyzulta (latanoprostene bunod ophthalmic solution) as a first-line treatment of open-angle glaucoma and ocular hypertension. Topics discussed include the use of topical prostaglandin analogs for lowering intraocular pressure (IOP), the release of nitric oxide by endothelial cells in Schlemm's canal to promote the aqueous outflow through the trabecular pathway, and Vyzulta in clinical trials.