A Sensitive ESI-MS HILIC Method for the Analysis of Acetylcholine and Choline.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read Online Read More Add to Saved list
  • Additional Information
    • Abstract:
      Hydrophilic interaction chromatography (HILIC) is a useful technique for the retention of polar analytes that offers a difference in selectivity compared with traditional reversed-phase (RP) chromatography. The highly volatile organic mobile phases used in HILIC provide increased electrospray ionization-mass spectrometry (ESI-MS) sensitivity. An Atlantis™ HILIC Silica column was used to develop a quantitative HILIC LC-MS method for the analysis of acetylcholine and choline. A limit of detection of 0.1 ng/ml was achieved for acetylcholine on a single quadrupole mass spectrometer. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of LC-GC Europe is the property of MJH Life Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)