An Automated Neoteric Approach to Trapping Compounds/Metabolites Implementing SPE Collection-Cartridges for Analysis.

Investigates an automated system for the collection of fractions and the separation of complex mixtures with the use of protonated solvents. Incorporation of SPE cartridges to trap the fractions from an HPLC UV-MS-NMR system; Elimination of the dry down of collected fractions; Decomposition of fractions during dry down; Elution of compounds absorbed onto the SPE cartridges in pure organic solvents.