THE STUDY OF MITOTIC ACTIVITY, ALKYLATING ACTION AND EFFECT ON TOPOISOMERASE PREPARATIONS K-19, DECOVIN AND K-20, OBTAINED ON THE BASIS OF COLCHICINE AND COLCHAMINE.

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    • Abstract:
      New drugs derived from colchicine K-19, decovin and K-20, have high antitumor activity and the ability to potentiate the effects of radiation. The elements of the mechanism of action of new drugs: mitotic activity, alkylating action, effects on topoisomerases I and II were studied. [ABSTRACT FROM AUTHOR]
    • Abstract:
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