Menu
×
West Ashley Library
Closed for Staff Day
Phone: (843) 766-6635
Wando Mount Pleasant Library
Closed for Staff Day
Phone: (843) 805-6888
Village Library
Closed for Staff Day
Phone: (843) 884-9741
St. Paul's/Hollywood Library
Closed for Staff Day
Phone: (843) 889-3300
Otranto Road Library
Closed for Staff Day
Phone: (843) 572-4094
Mt. Pleasant Library
Closed for Staff Day
Phone: (843) 849-6161
McClellanville Library
Closed for Staff Day
Phone: (843) 887-3699
Keith Summey North Charleston Library
Closed for Staff Day
Phone: (843) 744-2489
John's Island Library
Closed for Staff Day
Phone: (843) 559-1945
Hurd/St. Andrews Library
Closed for Staff Day
Phone: (843) 766-2546
Folly Beach Library
Closed for Staff Day
Phone: (843) 588-2001
Dorchester Road Library
Closed for Staff Day
Phone: (843) 552-6466
John L. Dart Library
Closed for Staff Day
Phone: (843) 722-7550
Baxter-Patrick James Island
Closed for Staff Day
Phone: (843) 795-6679
Main Library
Closed for Staff Day
Phone: (843) 805-6930
Bees Ferry West Ashley Library
Closed for Staff Day
Phone: (843) 805-6892
Miss Jane's Building (Edisto Library Temporary Location)
Closed
Phone: (843) 869-2355
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Mobile Library
9 a.m. - 5 p.m.
Phone: (843) 805-6909
Today's Hours
West Ashley Library
Closed for Staff Day
Phone: (843) 766-6635
Wando Mount Pleasant Library
Closed for Staff Day
Phone: (843) 805-6888
Village Library
Closed for Staff Day
Phone: (843) 884-9741
St. Paul's/Hollywood Library
Closed for Staff Day
Phone: (843) 889-3300
Otranto Road Library
Closed for Staff Day
Phone: (843) 572-4094
Mt. Pleasant Library
Closed for Staff Day
Phone: (843) 849-6161
McClellanville Library
Closed for Staff Day
Phone: (843) 887-3699
Keith Summey North Charleston Library
Closed for Staff Day
Phone: (843) 744-2489
John's Island Library
Closed for Staff Day
Phone: (843) 559-1945
Hurd/St. Andrews Library
Closed for Staff Day
Phone: (843) 766-2546
Folly Beach Library
Closed for Staff Day
Phone: (843) 588-2001
Dorchester Road Library
Closed for Staff Day
Phone: (843) 552-6466
John L. Dart Library
Closed for Staff Day
Phone: (843) 722-7550
Baxter-Patrick James Island
Closed for Staff Day
Phone: (843) 795-6679
Main Library
Closed for Staff Day
Phone: (843) 805-6930
Bees Ferry West Ashley Library
Closed for Staff Day
Phone: (843) 805-6892
Miss Jane's Building (Edisto Library Temporary Location)
Closed
Phone: (843) 869-2355
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Mobile Library
9 a.m. - 5 p.m.
Phone: (843) 805-6909
Patron Login
menu
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
Prophylaxe von Ubelkeit und Erbrechen nach Pelviskopien. Dolasetron oder MCP im Vergleich zu Plazebo. (German)
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- Author(s): Rüsch, D; Bernhardt, J; Wulf, H
- Source:
Anaesthesist; Oct1999, Vol. 48 Issue 10, p705-712, 8p- Subject Terms:
HETEROCYCLIC compounds; ANTIEMETICS; METOCLOPRAMIDE; INDOLE compounds; AMBULATORY surgery; CLINICAL trials; COMPARATIVE studies; GYNECOLOGIC surgery; INHALATION anesthesia; ISOFLURANE; LAPAROSCOPY; RESEARCH methodology; MEDICAL cooperation; NITROUS oxide; PELVIS; RESEARCH; EVALUATION research; RANDOMIZED controlled trials; INHALATION anesthetics; THERAPEUTICS - Source:
- Additional Information
- Alternate Title: [Prophylaxis of nausea and vomiting after pelviscopy. Dolasetron or MCP in comparison with placebo]. (English)
- Abstract:
Background: Gynaecological surgery including laparoscopy is frequently associated with PONV. Therefore, choosing an anaesthetic with only little side effects in operations eligible for outpatient surgery is at least as important as applying anaesthetics that enable fast-tracking.Study Goal: To assess the incidence and severity of PONV after balanced desflurane-N(2)O-anaesthesia and to compare the antiemetic efficacy of dolasetron or metoclopramide versus placebo.Methods: 120 ASA physical status I and II women aged 18 to 55 scheduled for elective laparoscopic surgery were enrolled. Anaesthesia was standardized: fentanyl (2 microg/kg), etomidate (0. 25 mg/kg) and succinylcholine (1 mg/kg) for induction and desflurane 3-5% et along with 30% O(2) in N(2)O, fentanyl (max. 0.1 mg/h) and cis-atracurium for maintenance. Patients were randomly allocated to receive one of the following: dolasetron 12.5 mg (group-D), metoclopramide 10 mg (group-M) or placebo (group-P).Results: Within the first 24 h, postoperative nausea (PON) and postoperative vomiting (POV) were reduced significantly in group D (38%/19%) and group M (36%/27%) compared to group P (69%/56%). Furthermore, PON and POV proved to be less intense in groups D and -M compared to group P: Episodes of severe nausea were recorded 17 times in 10 patients (17/10) in group P, compared to 5/4 in group M and 5/3 in group D, episodes of repeated vomiting 13 times in 8 patients (13/8) in group P, compared to 2/2 in group M and 2/1 in group D.Conclusions: Our results confirm the increased incidence of PONV after gynaecological laparoscopic surgery under balanced anaesthesia compared to the predicted rates. Both dolasetron and metoclopramide proved to be effective prophylactic measures. Given a PONV-incidence of 38% in group D and 39% in group M, it is doubtful, whether the anaesthetic technique chosen in this study is the most suitable regimen for ambulatory gynaecological laparoscopies. [ABSTRACT FROM AUTHOR] - Abstract: Copyright of Anaesthesist is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Alternate Title:
Contact CCPL
Copyright 2022 Charleston County Public Library Powered By EBSCO Stacks 3.3.0 [350.3] | Staff Login
No Comments.