Safer Pertussis Vaccines for Children: Trading Efficacy for Safety.

ATTITUDE (Psychology); BORDETELLA pertussis; DPT vaccines; CLINICAL drug trials; ENDOTOXINS; INJECTIONS; VACCINATION; PROFESSIONAL licenses; PARENT attitudes; CHILDREN

The article reports on the safety of the diphtheria, tetanus, and acellular pertussis (DTaP) vaccine examined through the review of data from the Vaccine Adverse Event Reporting System of the U.S. Centers for Disease Control and Prevention. Topics mentioned include the development and licensure of DTaP vaccines in the U.S. in the 1990s, common reactogenicity events reported, and the resurgence of pertussis in the country after the introduction of acellular vaccines.