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Efficacy and safety of the second generation cryoballoon ablation for the treatment of paroxysmal atrial fibrillation in patients over 75 years: a comparison with a younger cohort.
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- Author(s): Abugattas, Juan-Pablo; Iacopino, Saverio; Moran, Darragh; De Regibus, Valentina; Takarada, Ken; Mugnai, Giacomo; Ströker, Erwin; Coutiño-Moreno, Hugo Enrique; Choudhury, Rajin; Storti, Cesare; De Greef, Yves; Paparella, Gaetano; Brugada, Pedro; de Asmundis, Carlo; Chierchia, Gian-Battista
- Source:
EP: Europace; Nov2017, Vol. 19 Issue 11, p1798-1803, 6p- Subject Terms:
PERIPHERAL nerve injuries; ATRIAL fibrillation diagnosis; PHRENIC nerve; ATRIAL fibrillation; CATHETER ablation; COMPARATIVE studies; CRYOSURGERY; RESEARCH methodology; MEDICAL cooperation; PROGNOSIS; PULMONARY veins; RESEARCH; TIME; DISEASE relapse; PRODUCT design; EVALUATION research; TREATMENT effectiveness; PROPORTIONAL hazards models; RETROSPECTIVE studies; VASCULAR catheters; KAPLAN-Meier estimator; EQUIPMENT & supplies; SURGERY; WOUNDS & injuries - Source:
- Additional Information
- Subject Terms:
- Abstract:
Aims: In this double centre, retrospective study, we aimed to analyse the 1-year efficacy and safety of cryoballoon ablation (CB-A) in patients older than 75 years compared with those younger than 75-years old.Methods and Results: Fifty-three consecutive patients aged 75 years or older with drug-resistant paroxysmal AF (PAF) who underwent pulmonary vein isolation (PVI) by the means of second generation CB-A, were compared with 106 patients aged <75 years. The mean age in the study group (>75 years) was 78.19 ± 2.7 years and 58.97 ± 8.5 in the control group. At 1-year follow-up the global success rate was 83.6% and did not significantly differ between older (10/53) and younger patients (16/106) (81.1 vs. 84.9%, P = 0.54). Transient phrenic nerve palsy was the most common complication which occurred in eight patients in the younger group and in three in the older group (7.5 vs. 5.7%, respectively, P = 0.66).Conclusions: The results of our study showed that CB-A for the treatment of PAF is a feasible and safe procedure in elderly patients, with similar success and complications rates when compared with a younger population. [ABSTRACT FROM AUTHOR] - Abstract: Copyright of EP: Europace is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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