[Correction with zaditen of impaired activity of pancreatic digestive enzymes in sensitization and anaphylactic shock].

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  • Author(s): Ismailov SR;Ismailov SR
  • Source:
    Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2002 Sep-Oct; Vol. 65 (5), pp. 42-5.
  • Publication Type:
    English Abstract; Journal Article
  • Language:
    Russian
  • Additional Information
    • Transliterated Title:
      Korrektsiia zaditenom narusheniĭ aktivnosti pishchevaritel'nykh fermentov podzheludochnoĭ zhelezy pri sensibilizatsii i anafilakticheskom shoke.
    • Source:
      Publisher: Izd-vo Meditsina Country of Publication: Russia (Federation) NLM ID: 9215981 Publication Model: Print Cited Medium: Print ISSN: 0869-2092 (Print) Linking ISSN: 08692092 NLM ISO Abbreviation: Eksp Klin Farmakol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Moskva : Izd-vo Meditsina
    • Subject Terms:
      Immunization*/adverse effects; Anaphylaxis/*enzymology ; Histamine H1 Antagonists/*pharmacology ; Ketotifen/*pharmacology ; Pancreas/*enzymology ; alpha-Amylases/*metabolism; Anaphylaxis/prevention & control ; Animals ; Enzyme Activation ; Female ; Hydrolysis ; Male ; Rats ; alpha-Amylases/antagonists & inhibitors
    • Abstract:
      The effect of the antihistaminic drug zaditen on the activity of pancreatic digestive enzymes was studied in white rats under sensitization and anaphylactic shock conditions. The sensitization and anaphylaxis are accompanied by significant changes in the spectrum and activity of pancreatic enzymes (alpha amylase, protease complex, lipase), leading to disorders in the digestion and assimilation of proteins, fats, and carbohydrates. Zaditen reduced negative changes in the enzyme secretion system of pancreas under conditions of this pathology.
    • Accession Number:
      0 (Histamine H1 Antagonists)
      EC 3.2.1.1 (alpha-Amylases)
      X49220T18G (Ketotifen)
    • Publication Date:
      Date Created: 20030225 Date Completed: 20030317 Latest Revision: 20131121
    • Publication Date:
      20231215
    • Accession Number:
      12596514