[Sudden bilateral hearing loss disclosing meningeal carcinomatosis].

Surdité brusque bilatérale révélatrice d'une carcinomatose méningée.

Publisher: Masson Country of Publication: France NLM ID: 2984779R Publication Model: Print Cited Medium: Print ISSN: 0035-3787 (Print) Linking ISSN: 00353787 NLM ISO Abbreviation: Rev Neurol (Paris) Subsets: MEDLINE

Publication: Paris : Masson
Original Publication: Paris.

Carcinoma/*complications ; Carcinoma/*diagnosis ; Hearing Loss, Bilateral/*etiology ; Meningeal Neoplasms/*complications ; Meningeal Neoplasms/*diagnosis; Antineoplastic Agents/therapeutic use ; Carcinoma/secondary ; Cochlear Nerve/pathology ; Hearing Loss, Bilateral/pathology ; Humans ; Magnetic Resonance Imaging ; Male ; Meningeal Neoplasms/secondary ; Middle Aged ; Urinary Bladder Neoplasms/cerebrospinal fluid ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/pathology

We report the case of a patient presenting a sudden bilateral hearing loss. Four years before, a bladder carcinoma was resected and a chemotherapy was started. Gadolinium-enhanced magnetic resonance images revealed enhancement of both acoustic nerves. Cerebrospinal fluid analysis showed malignant cells consistent with the initial bladder cancer. Meningeal metastases from bladder carcinoma are extremely rare. Systemic chemotherapy and its low meningeal diffusion may enhance the incidence of this complication. Bilateral hearing loss is a rare initial manifestation of meningeal carcinomatosis.

0 (Antineoplastic Agents)

Date Created: 20021219 Date Completed: 20030205 Latest Revision: 20061115

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