Unutulan Elementin Bilinmeyen Mucizesi: "Magnezyum ve İmmünite". (Turkish)

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  • Author(s): Demirtürk, Zerrin; Esen, Figen
  • Source:
    Journal of the Turkish Society of Intensive Care / Türk Yogun Bakim Dernegi Dergisi; Aug2017, Vol. 15 Issue 2, p47-52, 6p
  • Additional Information
    • Alternate Title:
      The Unknown Miracle of the Forgotten Element: "Magnesium and Immunity". (English)
    • Abstract:
      This review aims to demonstrate the relation between magnesium and the immune system and their effect on inflammatory process in the critical patient, in addition to many other clinical uses of magnesium. Magnesium is the fourth most commonly found cation in the extracellular space in the human body and the second most common cation in the cell. Magnesium is an extremely important element when considering its role as an enzyme cofactor in many basic reactions, such as nucleic acid, protein synthesis and cell membrane stabilization. The most important features compared to other electrolytes is its effect on the immune system and living immunity. For each group of immunosuppressive or immunocompenent patients in intensive care unit, magnesium deficiency should be supported and in addition to other clinical benefits, the contribution of magnesium to the immune system should be kept in mind. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Bu derleme magnezyumun pek çok kullanım alanına ek olarak kritik hastada enflamasyon sürecine etkisi, immün sisteme olan katkısını göstermeyi amaçlamıştır. Magnezyum insan vücudunda ekstrasellüler alanda dördüncü sırada, intrasellüler olarak da ikinci olarak en sık bulunan katyonu olup; nükleik asit ve protein sentezi gibi birçok temel reaksiyonda enzim kofaktörü olarak rol alması, hücre membran stabilizasyonunu sağlaması gibi görevleri göz önüne alındığında son derece önemli bir elementtir. Diğer pek çok elektrolite kıyasla en önemli özelliği immün sisteme ve canlı immünitesine olan etkisidir. Yoğun bakımda yatan immünosüpresif ya da immünokompetan olan her grup hastada magnezyum eksikliği desteklenmeli ve pek çok yararına ek olarak magnezyumun immmün sisteme katkısı akılda tutulmalıdır. [ABSTRACT FROM AUTHOR]
    • Abstract:
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