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Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer.
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- Author(s): Cunningham, David; Pyrhonen, Seppo; James, Roger D.; Punt, Cornelis J.A.; Hickish, Tamas F.; Heikkila, Reino; Johannesen, Tom B.; Starkhammar, Hans; Topham, Clare A.; Awad, Lucile; Jacques, Christian; Herait, Patrice
- Source:
Lancet. 10/31/1998, Vol. 352 Issue 9138, p1413-1418. 6p. 1 Diagram, 4 Charts, 4 Graphs.
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- Additional Information
- Abstract:
Reports on a random trial to compare irinotecan, a topoisomerase I inhibitor, with supportive care alone for survival, quality of life, and other clinical variables in patients with metastatic colorectal cancer, and for whom fluorouracil has failed. Methods; Findings; Interpretation.
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