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Evaluation of the passive particle agglutination test in the serodiagnosis and follow-up of syphilis.
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- Additional Information
- Source:
Publisher: Oxford University Press Country of Publication: England NLM ID: 0370470 Publication Model: Print Cited Medium: Print ISSN: 0002-9173 (Print) Linking ISSN: 00029173 NLM ISO Abbreviation: Am J Clin Pathol Subsets: MEDLINE
- Publication Information:
Publication: 2016- : Oxford : Oxford University Press
Original Publication: Philadelphia [etc.] Lippincott [etc.]
- Subject Terms:
- Abstract:
We performed the present study to determine the rate of concordance of the fluorescent treponemal antibody absorption test (FTA-ABS) and of the microhemagglutination assay for antibodies to Treponema pallidum (MHA-TP) with the passive particle agglutination test (TP.PA) in patients with early syphilis and to observe the reactivity of the rapid plasma reagin (RPR), MHA-TP, and the TP.PA tests for 1 year after therapy. The study included 449 people who were given therapy if they had syphilis and followed up for 1 year. The rate of concordance of the TP.PA with the MHA-TP was 98.4%, and it was 98.9% with the FTA-ABS. During follow-up, a significant decrease of antibodies was found in 56%, 26%, and 70% of the patients when using the RPR, the MHA-TP, and the TP.PA, respectively. The TP.PA seems to be an adequate routine assay for the diagnosis of syphilis, being as sensitive as the FTA-ABS test in primary syphilis and as useful as the RPR test in monitoring therapy.
- Accession Number:
0 (Antibodies, Bacterial)
- Publication Date:
Date Created: 20011019 Date Completed: 20011025 Latest Revision: 20061115
- Publication Date:
20250114
- Accession Number:
10.1309/9TCQ-B1TA-38MV-R6UM
- Accession Number:
11605611
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