[Stem cells in adults].

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  • Author(s): Borge OJ;Borge OJ; Funderud S
  • Source:
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke [Tidsskr Nor Laegeforen] 2001 Aug 30; Vol. 121 (20), pp. 2398-401.
  • Publication Type:
    English Abstract; Journal Article; Review
  • Language:
    Norwegian
  • Additional Information
    • Transliterated Title:
      Stamceller hos voksne.
    • Source:
      Publisher: Norske Laegeforening Country of Publication: Norway NLM ID: 0413423 Publication Model: Print Cited Medium: Print ISSN: 0029-2001 (Print) Linking ISSN: 00292001 NLM ISO Abbreviation: Tidsskr Nor Laegeforen Subsets: MEDLINE
    • Publication Information:
      Publication: Oslo : Norske Laegeforening
      Original Publication: Chistiania : Alb. Cammermeyer, 1880-
    • Subject Terms:
      Hematopoietic Stem Cells/*physiology ; Stem Cells/*physiology; Adult ; Animals ; Bone Marrow Cells/metabolism ; Bone Marrow Cells/physiology ; Cell Differentiation ; Cloning, Organism ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/metabolism ; Humans ; Neuronal Plasticity ; Stem Cells/metabolism
    • Abstract:
      Background: We present a literature review of the plasticity observed by adult stem cells.
      Materials and Methods: We have reviewed the literature regarding stem cells from adults in order to summarise their ability to generate cells of other types than those of the tissue/organ from which they were isolated.
      Results: Adult stem cells have recently been demonstrated to terminally differentiate into cells of other tissues than those from which they were originally isolated. For example, bone marrow cells have been shown to generate liver, nerve, heart and skeletal muscle cells in addition to their well-known ability to produce blood and mesenchymal cells.
      Interpretation: Most studies demonstrate a proof-of-principle in animal models; much more research is needed before adult stem cells can be utilised in human medicine. However, the published reports are encouraging and give reasons for a cautious optimism with regard to future clinical use.
    • Number of References:
      30
    • Publication Date:
      Date Created: 20011018 Date Completed: 20011101 Latest Revision: 20080716
    • Publication Date:
      20250114
    • Accession Number:
      11603050