[From atopic eczema to respiratory allergy].

Dall'eczema atopico all'allergia respiratoria.

Publisher: Societa di medicina e scienze naturali di Parma Country of Publication: Italy NLM ID: 8106323 Publication Model: Print Cited Medium: Print NLM ISO Abbreviation: Acta Biomed Ateneo Parmense Subsets: MEDLINE

Publication: Parma : Societa di medicina e scienze naturali di Parma
Original Publication: Parma, Italia : La Società, 1981-

Asthma/*etiology ; Dermatitis, Atopic/*complications; Asthma/prevention & control ; Child ; Child, Preschool ; Dermatitis, Atopic/prevention & control ; Humans ; Infant

The prevalence of atopic eczema in childhood is increasing. This is probably related with a deviation of immune system to Th2 directed to allergen instead of Th2 directed to microorganisms. Atopic eczema is genetically linked, but its expression is principally determined by environmental factors, allergens and infections. In children with atopic eczema, the immune system is altered. The number of Langheran's cells is augmented. Th2 cells infiltrate the skin and produce cytokines which mediate both immediate and late allergic reaction. Most of eczematous children is allergic to food. A IgE-mediated reaction take place at the mucosal intestinal site. The food challenge test is the most reliable mean to identify offending foods. Soy formula can be used in the treatment of cow milk allergy. The tolerance of formulae based on cow milk hydrolysed protein should be tested under medical supervision in children with cow milk allergy. Prevention of atopic disease with dietary interventions has not been successful. To prevent asthma, the administration of immunotherapy in children with allergic rhinitis seems to be promising. In eczematous children with elevated total IgE and specific IgE to inhalant allergens, cetarizine seems to prevent onset of asthmatic symptoms.

Date Created: 20010627 Date Completed: 20011018 Latest Revision: 20130624

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