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Hepatitis delta virus genotypes I and III circulate associated with hepatitis B virus genotype F In Venezuela.
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- Additional Information
- Source:
Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Print ISSN: 0146-6615 (Print) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE
- Publication Information:
Publication: New York Ny : Wiley-Liss
Original Publication: New York, Liss.
- Subject Terms:
Biomarkers/
*analysis ;
DNA, Viral/
*analysis ;
Hepatitis Antibodies/
*analysis ;
Hepatitis B virus/
*genetics ;
Hepatitis D/
*complications ;
Hepatitis D/
*genetics ;
Hepatitis D, Chronic/
*complications ;
Hepatitis Delta Virus/
*genetics ;
Indians, South American/
*genetics ;
RNA, Viral/
*analysis;
Amino Acid Sequence ;
Base Sequence ;
Biomarkers/
blood ;
DNA, Viral/
blood ;
Genotype ;
Hepatitis Antibodies/
blood ;
Hepatitis Antibodies/
immunology ;
Hepatitis B/
blood ;
Hepatitis B/
virology ;
Hepatitis B Surface Antigens/
analysis ;
Hepatitis B Surface Antigens/
blood ;
Hepatitis B virus/
isolation & purification ;
Hepatitis D/
blood ;
Hepatitis D/
epidemiology ;
Hepatitis D/
virology ;
Hepatitis D, Chronic/
blood ;
Hepatitis D, Chronic/
epidemiology ;
Hepatitis D, Chronic/
virology ;
Hepatitis Delta Virus/
isolation & purification ;
Humans ;
Indians, South American/
classification ;
Phylogeny ;
Polymerase Chain Reaction ;
RNA, Viral/
blood ;
Sequence Alignment ;
Venezuela/
epidemiology - Abstract:
The genotypes of hepatitis B (HBV) and delta (HDV) viruses circulating among Venezuelan Amerindian populations, where these viruses are endemic, were determined by sequencing of PCR amplified products from HBsAg positive sera. HDV genotype I (n = 7, 6 from West Amerindians), and III (n = 5, 4 from South Amerindians), were found. Only one HDV genotype I isolate was associated with HBV genotype D, 4 HDV genotype I and 2 HDV genotype III infected individuals were co-infected with HBV genotype F. The failure to detect the South American HDV genotype III in West Amerindians might be related to the outbreak of fulminant hepatitis with high mortality rate occurred between 1979 and 1982, probably affecting more the Amerindians infected with HDV genotype III. These results suggest the circulation of HDV genotype I among Amerindians, probably introduced through European immigrations, and that this HDV genotype is able to replicate in association with HBV genotype F.
(Copyright 2001 Wiley-Liss, Inc.)
- Accession Number:
0 (Biomarkers)
0 (DNA, Viral)
0 (Hepatitis Antibodies)
0 (Hepatitis B Surface Antigens)
0 (RNA, Viral)
- Publication Date:
Date Created: 20010626 Date Completed: 20010913 Latest Revision: 20190901
- Publication Date:
20221213
- Accession Number:
10.1002/jmv.1058
- Accession Number:
11424126
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