A simple cuff electrode for nerve recording and stimulation in acute experiments on small animals.

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  • Author(s): Fenik V;Fenik V; Fenik P; Kubin L
  • Source:
    Journal of neuroscience methods [J Neurosci Methods] 2001 Apr 30; Vol. 106 (2), pp. 147-51.
  • Publication Type:
    Journal Article; Research Support, U.S. Gov't, P.H.S.
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7905558 Publication Model: Print Cited Medium: Print ISSN: 0165-0270 (Print) Linking ISSN: 01650270 NLM ISO Abbreviation: J Neurosci Methods Subsets: MEDLINE
    • Publication Information:
      Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press.
    • Subject Terms:
      Electrodes*; Electrophysiology/*instrumentation ; Hypoglossal Nerve/*physiology ; Laryngeal Nerves/*physiology ; Phrenic Nerve/*physiology; Animals ; Equipment Design ; Rats ; Rats, Sprague-Dawley
    • Abstract:
      We describe a cuff-type electrode specifically designed for recording from, and electrical stimulation of, cut nerves in acute experiments on small animals. Unlike existing designs of cuff electrodes, it is simple to manufacture, inexpensive and takes little time to implant. The electrode was tested on the hypoglossal, phrenic, recurrent laryngeal, and superior laryngeal nerves in anesthetized rats. It provides satisfactory signal-to-noise ratios (3.0+/-0.8 (mean+/-S.D.)) for hypoglossal and 5.4+/-2.1 for phrenic nerve activity and stable recording over the time course of a typical acute experiment. It eliminates or minimizes the problems with recording stability and space availability associated with conventional hook-type electrodes, and reduces experiment preparation time. This should facilitate neurophysiological experiments on small rodents involving complex protocols that include recording from, and/or stimulation of, multiple nerves.
    • Grant Information:
      P50 HL060287 United States HL NHLBI NIH HHS; HL-60287 United States HL NHLBI NIH HHS
    • Publication Date:
      Date Created: 20010428 Date Completed: 20010705 Latest Revision: 20190901
    • Publication Date:
      20240829
    • Accession Number:
      10.1016/s0165-0270(01)00340-5
    • Accession Number:
      11325434