Analysis of the Generation and Segregation of Propagons: Entities that Propagate the [PSI[sup +]] Prion in Yeast.

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    • Abstract:
      Demonstrates considerable clonal variation in the apparent numbers of propagons between different yeast strains, between different cultures of the same yeast strain, and between different cells of the same culture. Evidence that propagon generation is blocked by growth in guanidine hydrochloride; Bias toward retention of propagons in mother cells.