The association of dietary folate, B6, and B12 with cardiovascular mortality in Spain: an ecological analysis.

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  • Additional Information
    • Source:
      Publisher: American Public Health Association Country of Publication: United States NLM ID: 1254074 Publication Model: Print Cited Medium: Print ISSN: 0090-0036 (Print) Linking ISSN: 00900036 NLM ISO Abbreviation: Am J Public Health Subsets: MEDLINE
    • Publication Information:
      Publication: Washington, DC : American Public Health Association
      Original Publication: New York [etc.]
    • Subject Terms:
      Cardiovascular Diseases/*mortality ; Folic Acid Deficiency/*complications ; Vitamin B 12 Deficiency/*complications ; Vitamin B 6 Deficiency/*complications; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Nutrition Surveys ; Poisson Distribution ; Risk Factors ; Spain/epidemiology
    • Abstract:
      Objectives: This study assessed the association of dietary folate, vitamin B6, and vitamin B12 with cardiovascular mortality.
      Methods: Poisson regression analyses assessed coronary/cerebrovascular mortality rates via nutrient data obtained from the National Nutrition Survey, which recorded 7-day food intakes from a national sample of 21,155 households.
      Results: In regard to coronary mortality, male and female rate ratios (highest vs lowest quintile) were 0.83 (95% confidence interval [CI] = 0.77, 0.91) and 0.95 (95% CI = 0.86, 1.05), respectively, for folate and 0.74 (95% CI = 0.65, 0.84) and 0.86 (95% CI = 0.73, 0.99), respectively, for B12. Intake of folate and B6 (but not B12) was significantly associated with cerebrovascular mortality.
      Conclusions: B vitamins are associated with cardiovascular mortality in the general population.
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    • Publication Date:
      Date Created: 20001013 Date Completed: 20001019 Latest Revision: 20190514
    • Publication Date:
      20221213
    • Accession Number:
      PMC1446360
    • Accession Number:
      10.2105/ajph.90.10.1636
    • Accession Number:
      11030004