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Isolation and characterization of cytotoxic saponin chloromaloside A from Chlorophytum malayense.
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- Additional Information
- Source:
Publisher: George Thieme Country of Publication: Germany NLM ID: 0066751 Publication Model: Print Cited Medium: Print ISSN: 0032-0943 (Print) Linking ISSN: 00320943 NLM ISO Abbreviation: Planta Med Subsets: MEDLINE
- Publication Information:
Publication: Stuttgart ; New York : George Thieme
Original Publication: Stuttgart, Hippokrates Verlag.
- Subject Terms:
- Abstract:
A cytotoxic steroidal glycoside was isolated from Chlorophytum malayense Ridley and its structure was characterized as a known compound, neohecogenin 3-O-beta-D-glucopyranosyl(1-->2)-[beta-D-xylopyranosyl(1-->3)]-beta-D- glucopyranosyl(1-->4)-beta-D-galactopyranoside (chloromaloside A). The structural identification was performed using 2D-NMR and LC/MS/MS analysis. The previous, erroneously assigned 1H-NMR spectral data were revised whereas the published 13C-NMR spectral assignments were confirmed. This compound showed in vitro cytotoxicity against several human cancer cell lines.
- Accession Number:
0 (Antineoplastic Agents, Phytogenic)
0 (Saponins)
0 (Spirostans)
133024-11-0 (chloromaloside A)
- Publication Date:
Date Created: 20000914 Date Completed: 20001018 Latest Revision: 20061115
- Publication Date:
20221213
- Accession Number:
10.1055/s-2000-8600
- Accession Number:
10985095
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