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Including a subject-paced trial may make the PASAT more acceptable for MS patients.
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- Author(s): Bosnes, O.; Dahl, O.‐P.; Almkvist, O.
- Source:
Acta Neurologica Scandinavica; Oct2015, Vol. 132 Issue 4, p219-225, 7p- Subject Terms:
- Source:
- Additional Information
- Abstract: The Paced Auditory Serial Addition Test (PASAT) is regularly used in the evaluation of cognition in multiple sclerosis (MS). However, the test may impose frustration, distress, and anxiety in patients, which may result in refusal to participate by many patients. Objectives In this study, a subject- and experimenter-paced PASAT was compared and analyzed, with regard to independent measures of cognitive functions, as well as disability, fatigue, depression, and anxiety. Methods A population-based sample of patients with MS ( n = 34; mean age 47.2 ± 8.6) was examined with the PASAT, including a subject-paced condition, in addition to the standard experimenter-paced conditions using three levels of interstimuli intervals (ISI: 3.0, 2.5, and 2.0 s). A comprehensive set of neuropsychological tests, measures of disease severity, fatigue, anxiety, and depression were studied as potentially associated factors. Results Subject- and experimenter-paced PASAT performance correlated significantly and the subject-paced administration correlated even higher with measures of information processing speed, executive function, attention, and working memory than standard experimenter-paced administration of PASAT. Discussion The associations between PASAT performance and measures of fatigue, anxiety, and depression were not significant. Conclusion The results indicate that the altered PASAT procedure measures the same cognitive functions in MS as the standard procedure. At the same time, the altered procedure may make the PASAT more user-friendly for patients with MS. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Acta Neurologica Scandinavica is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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