Osteoarthritis: a review of treatment options.

Osteoarttiritis (OA) is the most common form of arthritis and the leading cause of disability in the United States, especially among oider adults. Treatment options have primarily focused on alieviating the pain often associated with this condition. Acetaminophen and nonsteroidal antiinflammatory drugs (NSAIDs) are often employed for relief of mild-to-moderate pain associated with OA. NSAIDs are typically more effective than acetaminophen; however, because of adverse effects associated with long-term use of NSAIDs, acetaminophen is considered first-line therapy. Safety concems over traditional pharmacotherapeutic agents used in the management of OA, such as NSAIDs and opioids, have led healthcare professionals to seek other options. Trials of diseasemodulating agents that focus on preventing further damage to the joints have the potential to change how this disease state is managed. This article reviews non pharmacologie and pharmacologie approaches to management of OA of the knee and hip. [ABSTRACT FROM AUTHOR]