LACTATE VALUE MEASUREMENT WITH MAGNETIC RESONANCE SPECTROSCOPY IN THE VASTUS MEDIALIS MUSCLE BEFORE AND AFTER EXERCISE. (Slovak)

Introduction: Magnetic resonance spectroscopy (MRS) is a non-invasive examination which enables identification and quantification of metabolites in tissues. Compared to conventional magnetic resonance imaging (MRI), MRS provides physiological and biochemical information on the composition of tissues in the body by presenting metabolites in the magnetic resonance spectra. Purpose: The purpose of this article is to show relative concentrations of lactate in the vastus medialis muscle on the MR spectra before, immediately after and one hour after physical exercise. Methods: Review of current literature and implementation of MRS in the vastus medialis muscles in five physically well-prepared athletes by using the STEAM pulse sequence. Measurements were conducted on a magnetic resonance tomograph Philips Achieva 3.0T TX at the Centre of Clinical Physiology at the Faculty of Medicine. Results: In four out of five participants, the MR spectra showed a significant increase of lactate immediately after the exercise and a decrease after one hour, compared to the lactate levels before the physical exercise. Discussion and conclusion: Literature review showed fluctuations in lactate levels – from lower levels while resting to higher levels after exercise, which is in line with our findings. [ABSTRACT FROM AUTHOR]

Uvod: Magnetno resonančna spektroskopija (MRS) je neinvazivna preiskava, ki omogoča identifikacijo in količinsko opredelitev metabolitov v tkivih. MRS za razliko od klasične magnetno resonančne (MR) preiskave omogoča pridobitev fizioloških in biokemičnih informacij o sestavi tkiv v telesu s prikazom metabolitov v MR spektrih. Namen: Namen članka je na MR spektrih prikazati relativne koncentracije laktata v mišici vastus medialis pred fizično obremenitvijo, takoj po obremenitvi in eno uro po njej. Metode: Pregled dosedanje literature in izvedba MRS na mišici vastus medialis na petih fizično dobro pripravljenih športnikih z uporabo pulznega zaporedja STEAM. Meritve so bile narejene na MR tomografu Philips Achieva 3.0T TX na Centru za klinično fiziologijo na Medicinski fakulteti. Rezultati: Na MR spektrih sva pri štirih izmed petih udeležencih prikazala pomembno povišanje vrednosti laktata takoj po obremenitvi in padec vrednosti laktata v eni uri po njej, v primerjavi z njegovo vrednostjo pred fizično obremenitvijo. Razprava in zaključki: Pregled literature kaže na nihanje vrednosti laktata, vse od nižjih koncentracij v mirovanju do višjih po fizični obremenitvi, kar je skladno z najinimi rezultati. [ABSTRACT FROM AUTHOR]

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