Biological Activities of Some Transition Metal Complexes Derived from Floral Fragrances.

Transition metal complexes containing a tridentate N, S, and O donor ligand i.e. 3,7-dimethyl-7-hydroxyoctane thiosemicarbazone (DHOTSC) have been synthesized and characterized by elemental analysis, molar conductance, magnetic susceptibility measurements and various spectral studies. The ligand DHOTSC acts as ML2 type complexes M = Cu(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II), L = DHOTSC. The ligand DHOTSC acts as tridentate ligand in all complexes. The N, S and O atoms of ligand are involved in coordination to metal ion. All the newly synthesized metal complexes as well as the ligand were screened for their antifungal and antibacterial activity. The activities of the complexes are stronger than those of ligand DHOTSC itself. [ABSTRACT FROM AUTHOR]

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