[Electrofocusing of immunoglobulin G that reacts positively in the sedimentation reaction for cancer].

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  • Author(s): Protsenko BA; Korotkoruchko VP; Sen'ko LN
  • Source:
    Ukrains'kyi biokhimichnyi zhurnal [Ukr Biokhim Zh] 1976 Sep-Oct; Vol. 48 (5), pp. 626-8.
  • Publication Type:
    English Abstract; Journal Article
  • Language:
    Ukrainian
  • Additional Information
    • Transliterated Title:
      Elektrofokusuvannia imunohlobulinu G, shcho pozytyvno reahuie v osadoviĭ reaktsiï na rak
    • Source:
      Publisher: Izdatelstvo Naukova Dumka Country of Publication: Ukraine NLM ID: 0414153 Publication Model: Print Cited Medium: Print ISSN: 0041-610X (Print) NLM ISO Abbreviation: Ukr Biokhim Zh Subsets: MEDLINE
    • Publication Information:
      Original Publication: Kyiv : Izdatelstvo Naukova Dumka
    • Subject Terms:
      Isoelectric Focusing*; Immunoglobulin G/*analysis; Blood Sedimentation ; Chromatography, DEAE-Cellulose ; Humans ; Immunoelectrophoresis ; Multiple Myeloma/immunology
    • Abstract:
      Immunoglobulin G from the serum of patients with myeloma and positively reacting in the sedimentary test for cancer (PPR-STC) was purified by DEAE-Spehadex A-50 and KM-cellulose chromotography and studied by the method of isoelectrofocusing; Application of 1% ampholine within the pH gradient 3.0-10.0 shows the difference between the isoelectric spectra of immunoglobulin G from the donor and from a patient with myeloma. The PPR-STC isoelectric point located in the zone of pH 8.4 is determined. No subfraction with pH 8.4 is observed in the fraction of the donor immunoglobulin G.
    • Accession Number:
      0 (Immunoglobulin G)
    • Publication Date:
      Date Created: 19760901 Date Completed: 19770512 Latest Revision: 20061115
    • Publication Date:
      20240829
    • Accession Number:
      1021918