The association of inadequate mid-pregnancy weight gain and preterm birth in twin pregnancies.

RISK factors in premature labor; ACADEMIC medical centers; CHI-squared test; CONFIDENCE intervals; FISHER exact test; LONGITUDINAL method; MULTIPLE pregnancy; MULTIVARIATE analysis; T-test (Statistics); WEIGHT gain; LOGISTIC regression analysis; RETROSPECTIVE studies; DATA analysis software; DESCRIPTIVE statistics

Objective:To determine whether inadequate gestational weight gain in the second trimester in twin pregnancies is associated with an increased risk of preterm birth (PTB) at <32 weeks.Study Design:Retrospective cohort study including 489 twin pregnancies delivered between 2001 and 2013. Rates of weight gain at different gestational ages were compared with Institute of Medicine guidelines.Result:An inadequate rate of weight gain at <20 weeks was not associated with PTB. Patients with inadequate rates of weight gain at 20 to 28 weeks had a higher risk of PTB at <32 weeks (37.6%) compared to those with adequate weight gain (15.2%) (P<0.001). In multivariate analysis, women with inadequate weight gain at 20 to 28 weeks were 2.8 times more likely to deliver at <32 weeks (95% confidence interval 1.65 to 4.81).Conclusion:Inadequate gestational weight gain at 20 to 28 weeks in twin pregnancies was the strongest predictor of PTB at <32 weeks. This represents an optimal time for interventions to improve weight gain and potentially decrease rates of PTB. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Perinatology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)