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Multiple System Atrophy: Pathology, Pathogenesis, and Path Forward.

• Authors : Ndayisaba A; 1Division of Movement Disorders, Ann Romney Center for Neurologic Diseases, American Parkinson Disease Association (APDA) Center for Advanced Research and MSA Center of Excellence, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA; email: .

• Source: Annual review of pathology [Annu Rev Pathol] 2024 Oct 15. Date of Electronic Publication: 2024 Oct 15.Publisher: Annual Reviews Country of Publication: United States NLM ID: 101275111 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice.

• Authors : Galbiati M; Dipartimento di Scienze Farmacologiche e Biomolecolari 'Rodolfo Paoletti', Dipartimento di Eccellenza 2018-2027, Università degli Studi di Milano, Milan, Italy. .; Meroni M

Subjects: Bulbo-Spinal Atrophy, X-Linked*/Bulbo-Spinal Atrophy, X-Linked*/Bulbo-Spinal Atrophy, X-Linked*/drug therapy ; Bulbo-Spinal Atrophy, X-Linked*/Bulbo-Spinal Atrophy, X-Linked*/Bulbo-Spinal Atrophy, X-Linked*/genetics ; Muscular Atrophy, Spinal*

• Source: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2023 Mar; Vol. 20 (2), pp. 524-545. Date of Electronic Publication: Publisher: Springer Country of Publication: United States NLM ID: 101290381 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Multiple system atrophy pathology is associated with primary Sjögren's syndrome.

• Authors : Conway KS; Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Camelo-Piragua S

Subjects: Autoimmune Diseases/Autoimmune Diseases/Autoimmune Diseases/*complications ; Brain/Brain/Brain/*pathology ; Multiple System Atrophy/Multiple System Atrophy/Multiple System Atrophy/*pathology

• Source: JCI insight [JCI Insight] 2020 Aug 06; Vol. 5 (15). Date of Electronic Publication: 2020 Aug 06.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium:

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Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology.

• Authors : Yiyang Qin; Wenzhen Zhu; Tingting Guo

• Source: Neural Regeneration Research; Sep2025, Vol. 20 Issue 9, p2655-2666, 12p

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CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis.

• Authors : Janzen E; Institute of Human Genetics, Center for Molecular Medicine Cologne, Institute for Genetics, University of Cologne, Cologne, Germany.; Mendoza-Ferreira N

Subjects: Calcium-Binding Proteins/Calcium-Binding Proteins/Calcium-Binding Proteins/*metabolism ; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*physiology ; Microfilament Proteins/Microfilament Proteins/Microfilament Proteins/*physiology

• Source: Brain : a journal of neurology [Brain] 2018 Aug 01; Vol. 141 (8), pp. 2343-2361.Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN:

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Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology.

• Authors : Thompson LW; School of Biology, University of St Andrews, BSRC Complex, North Haugh St Andrews, KY16 9ST, UK.; Morrison KD

Subjects: Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/*pathology ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*metabolism ; SMN Complex Proteins/SMN Complex Proteins/SMN Complex Proteins/*metabolism

• Source: Journal of cell science [J Cell Sci] 2018 Apr 17; Vol. 131 (8). Date of Electronic Publication: 2018 Apr 17.Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Electronic Cited Medium: Internet ISSN:

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ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice.

• Authors : Abera MB; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, F. Edward Hebert School of Medicine, Bethesda, Maryland, USA.; Xiao J

Subjects: Ubiquitination*; Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/*drug therapy ; Survival of Motor Neuron 1 Protein/Survival of Motor Neuron 1 Protein/Survival of Motor Neuron 1 Protein/*chemistry

• Source: JCI insight [JCI Insight] 2016 Nov 17; Vol. 1 (19), pp. e88427. Date of Electronic Publication: 2016 Nov 17.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium:

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Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology.

• Authors : Qin Y; Guangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), Guangdong-HongKong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong Province, China.; Zhu W

• Source: Neural regeneration research [Neural Regen Res] 2025 Sep 01; Vol. 20 (9), pp. 2655-2666. Date of Electronic Publication: 2024 Jun 26.Publisher: Wolters Kluwer Health, Medknow Country of Publication: India NLM ID: 101316351 Publication Model: Print-Electronic Cited Medium: Print

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[Posterior cortical atrophy. Pathology, diagnosis and treatment of a rare form of dementia].

• Authors : Ortner M; Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland, .; Kurz A

Subjects: Brain/Brain/Brain/*pathology ; Cognitive Behavioral Therapy/Cognitive Behavioral Therapy/Cognitive Behavioral Therapy/*methods ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*diagnosis

• Source: Der Nervenarzt [Nervenarzt] 2015 Jul; Vol. 86 (7), pp. 833-9.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0400773 Publication Model: Print Cited Medium: Internet ISSN: 1433-0407

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Research data from University of Cambridge, Department of Pharmacology update understanding of atrophy pathology.

• Source: Health & Medicine Week. 2008, pages. 2671

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