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Epigenetic therapies targeting histone lysine methylation: complex mechanisms and clinical challenges

• Authors : Gold, Sarah; Shilatifard, Ali

• Source: Journal of Clinical Investigation. October 15, 2024, Vol. 134 Issue 20

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PRMT5-mediated FUBP1 methylation accelerates prostate cancer progression

• Authors : Yan, Weiwei; Liu, Xun; Qiu, Xuefeng

• Source: Journal of Clinical Investigation. September 15, 2024, Vol. 134 Issue 18

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DNA methylation-mediated Rbpjk suppression protects against fracture nonunion caused by systemic inflammation

• Authors : Xiao, Ding; Fang, Liang; Liu, Zhongting

• Source: Journal of Clinical Investigation. February, 2024, Vol. 134 Issue 3

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Chronic graft-versus-host disease detected by tissue-specific cell-free DNA methylation biomarkers

• Authors : Avni, Batia; Neiman, Daniel; Shaked, Elior

• Source: Journal of Clinical Investigation. January 15, 2024, Vol. 134 Issue 2

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FTO fuels diabetes-induced vascular endothelial dysfunction associated with inflammation by erasing [m.sup.6]A methylation of TNIP1

• Authors : Zhou, Chuandi; She, Xinping; Gu, Chufeng

• Source: Journal of Clinical Investigation. October, 2023, Vol. 133 Issue 19

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Reduced methylation correlates with diabetic nephropathy risk in type 1 diabetes

• Authors : Khurana, Ishant; Kaipananickal, Harikrishnan; Maxwell, Scott

• Source: Journal of Clinical Investigation. February 15, 2023, Vol. 133 Issue 4

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PRMT5-mediated FUBP1 methylation accelerates prostate cancer progression.

• Authors : Weiwei Yan; Xun Liu; Xuefeng Qiu

Subjects: PROSTATE cancer; CANCER invasiveness; METHYLATION

• Source: Journal of Clinical Investigation. 9/17/2024, Vol. 134 Issue 18, p1-18. 18p.

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TET repression and increased DNMT activity synergistically induce aberrant DNA methylation

• Authors : Takeshima, Hideyuki; Niwa, Tohru; Yamashita, Satoshi

• Source: Journal of Clinical Investigation. October, 2020, Vol. 130 Issue 10, p5370, 10 p.

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Genome-wide plasma DNA methylation features of metastatic prostate cancer

• Authors : Wu, Anjui; Cremaschi, Paolo; Wetterskog, Daniel

• Source: Journal of Clinical Investigation. April, 2020, Vol. 130 Issue 4, p1991, 10 p.

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Methylation of immune synapse genes modulates tumor immunogenicity

• Authors : Berglund, Anders; Mills, Matthew; Putney, Ryan M.

• Source: Journal of Clinical Investigation. February, 2020, Vol. 130 Issue 2, p974, 7 p.

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