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A nuclear genome assembly of an extinct flightless bird, the little bush moa.
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- Additional Information
- Source:
Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
- Publication Information:
Original Publication: Washington, DC : American Association for the Advancement of Science, [2015]-
- Subject Terms:
- Abstract:
We present a draft genome of the little bush moa ( Anomalopteryx didiformis )-one of approximately nine species of extinct flightless birds from Aotearoa, New Zealand-using ancient DNA recovered from a fossil bone from the South Island. We recover a complete mitochondrial genome at 249.9× depth of coverage and almost 900 megabases of a male moa nuclear genome at ~4 to 5× coverage, with sequence contiguity sufficient to identify more than 85% of avian universal single-copy orthologs. We describe a diverse landscape of transposable elements and satellite repeats, estimate a long-term effective population size of ~240,000, identify a diverse suite of olfactory receptor genes and an opsin repertoire with sensitivity in the ultraviolet range, show that the wingless moa phenotype is likely not attributable to gene loss or pseudogenization, and identify potential function-altering coding sequence variants in moa that could be synthesized for future functional assays. This genomic resource should support further studies of avian evolution and morphological divergence.
- Accession Number:
0 (DNA Transposable Elements)
- Publication Date:
Date Created: 20240523 Date Completed: 20240523 Latest Revision: 20240523
- Publication Date:
20240524
- Accession Number:
10.1126/sciadv.adj6823
- Accession Number:
38781323
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