SAVREMENI POGLED NA MEHANIZME EPITELIJALNE DIFERENCIJACIJE ORALNE MUKOZE U NORMALNIM I PATOLOŠKIM PROCESIMA. (Bosnian)

MODERN VIEW ON MECHANISMS OF EPITHELIUM DIFFERENTIATION OF THE ORAL MUCOSA IN NORMAL AND PATHOLOGICAL PROCESSES. (English)

Background:In everyday clinical practice, patients who seek dental care in case of oral mucosa diseases are one of the most difficult categories of patients due to difficulties in diagnosis and treatment. Materials and methods:The review and analysis of scientific and medical literature based on the Scopus, Web of Science, MedLine, PubMed, NCBI databases, the study of which does not exceed 5 years, including literature reviews and the results of clinical trials. Results:Changes in the oral mucosa can be clearly specific. Clinicians can make the correct diagnosis and determine the tactics of treatment by appearance. However, in most cases the diagnosis of diseases with this anatomical location is complicated, because the clinical picture is nonspecific and often burdened with additional local and general adverse factors. A detailed clinical examination and additional research methods are required to establish the correct diagnosis. Diagnosis of oral mucosa diseases is based on a careful assessment of clinical and laboratory data. Conclusions:Taking into account the prevalence of diseases of the oral mucosa, of particular interest is the question of the course of the process of differentiation of the epithelium of various anatomical zones in the norm and the mechanisms of restructuring of the cellular composition in pathological processes, with the cops of objectifying the diagnosis, predicting the course of the disease and pathogenetically substantiated treatment. [ABSTRACT FROM AUTHOR]

Uvod:U svakodnevnoj kliničkoj praksi pacijenti koji traže stomatološku negu u slučaju oboljenja oralne sluzokože su jedna od najtežih kategorija pacijenata zbog komplikacija u dijagnostici i lečenju. Materijali i metode:Pregled i analiza naučne i medicinske literature zasnovana na bazama podataka Scopus, Veb of Science, MedLine, PubMed, NCBI, čija starost ne prelazi 5 godina, uključujuc'i pregledne radove i rezultate kliničkih ispitivanja. Rezultati:. Promene na oralnoj sluznokoži mogu biti jako specifične. Kliničari mogu postaviti ispravnu dijagnozu i izgledom odrediti proceduru lečenja. Međutim, u vec'ini slučajeva dijagnoza bolesti sa ovom anatomskom lokacijom je komplikovana, jer je klinička slika nespecifična i često su pridodati lokalni i opšti nepovoljni faktori. Za postavljanje tačne dijagnoze neophodan je detaljan klinički pregled i dodatne metode istraživanja. Dijagnoza bolesti oralne sluzokože zasniva se na pažljivoj proceni kliničkih i laboratorijskih podataka. Zaključak:Uzimajuc'i u obzir rasprostranjenost oboljenja oralne sluzokože, posebno je interesantno pitanje toka procesa diferencijacije epitela različitih anatomskih zona i mehanizama restrukturiranja c'elijskog sastava u patološkim procesima, koji objektivizuju dijagnozu, predviđaju tok bolesti i patogenetski potkrepljeni tretman. [ABSTRACT FROM AUTHOR]

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